Interaction between tissue factor pathway inhibitor and factor V levels on the risk of venous thrombosis
نویسندگان
چکیده
منابع مشابه
Low levels of tissue factor pathway inhibitor (TFPI) increase the risk of venous thrombosis.
There is now strong experimental evidence that tissue factor pathway inhibitor (TFPI) is a critical inhibitor to modulate tissue factor-induced coagulation, but the role of TFPI as a risk factor for thrombosis is yet to be to be determined. This study investigated the role of low TFPI levels for the development of deep-vein thrombosis (DVT). We determined TFPI activity and TFPI-free and total a...
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Full-length tissue factor pathway inhibitor (TFPI) is assumed to be biologically more important than truncated TFPI because of its stronger anticoagulant effect in the diluted prothrombin time (dPT) assay. We have developed a dPT-based assay for TFPI anticoagulant activity. Here, we report the effect of hormonal state on TFPI anticoagulant activity and whether TFPI anticoagulant activity assess...
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Patients with coagulation factor(s) deficiency who use coagulation therapy are susceptible to forming inhibitors against coagulation factor(s). In this survey we detected factor V and VIII inhibitor in ten patients with combined deficiency of factors V and VIII from north east of Iran (Khorassan province). It was revealed in our survey that eight patients had both factor V and factor VIII i...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2010
ISSN: 1538-7933,1538-7836
DOI: 10.1111/j.1538-7836.2010.03805.x